Podocalyxin-Like (PODXL) Peptide
PODXL
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN981930
Quick Overview for Podocalyxin-Like (PODXL) Peptide (ABIN981930)
Target
PODXL
(Podocalyxin-Like (PODXL))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PODXL antibody (Catalog #: ARP44730_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Podocalyxin-Like (PODXL) peptide
PODXL Reactivity: Human, Rat, Mouse, Dog Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PODXL (Podocalyxin-Like (PODXL))
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Background
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PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Alias Symbols: Gp200, MGC138240, PCLP, PC, PCLP-1
Protein Interaction Partner: SELL,SLC9A3R2,SELL,SLC9A3R2
Protein Size: 558 -
Molecular Weight
- 56 kDa
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Gene ID
- 5420
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NCBI Accession
- NM_001018111, NP_001018121
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UniProt
- A6NHX8
Target
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